PCOS (Now Called PMOS): A Metabolic and Hormone Approach

Painful cycles, heavy bleeding, mood swings, low energy and stubborn weight are not “all in your head.” Dr. Matt Chalmers has spent 15 years helping women fix the metabolic and hormone issues behind PCOS/PMOS, in Frisco, TX and by telehealth across the US.

What Is PCOS/PMOS, Really?

The easiest way to explain it: the nutrients your body needs can no longer get into the organs that need them. When the raw materials can’t get into the cell, the organ can’t work the way it was designed to. One of the biggest reasons this happens in PCOS is insulin resistance.

In 2026, PCOS was officially renamed PMOS, polyendocrine metabolic ovarian syndrome. The new name recognizes that this is a metabolic and hormone condition, not just an ovary problem. That’s how we have always treated it. Reset the metabolic hormones, insulin and glucagon, and get nutrients back where they belong, and the body works the way it was designed to.

Our Approach: Test, Reset, Rebuild

1. Test

A consult and targeted labs, including fasting insulin, A1C, iron, testosterone, estradiol and SHBG, customized to you.

2. Reset

Correct insulin resistance with a low-glycemic way of eating, key nutrients and, when you choose, GLP-1 peptides for a faster reset.

3. Rebuild

Balance hormones and dial in minerals, sleep, stress and exercise so your body stays headed in the right direction.

Why Birth Control Alone Isn’t the Answer

The women I see usually tell the same story. They came in with painful periods, heavy bleeding, mood changes around their cycle, low energy or weight they couldn’t lose. They were put on birth control, maybe told to take Advil or Midol, and when their labs “looked fine,” they were told it was in their head.

Birth control does not fix women’s hormones. It masks the cycle while the metabolic problem underneath keeps growing. If your plan doesn’t address insulin resistance and a low-glycemic diet, you won’t get the results that come from treating PCOS/PMOS as the metabolic issue it is.

After 15 years of working with women on their hormones, I fix problems every day that women were told aren’t real or that no one could help with. You deserve better than that, and it is not that hard to help.

What We Test and How the Program Works

Our Standard Labs

  • Fasting insulin and A1C
  • Iron and ferritin
  • Testosterone, total and free
  • Estradiol and SHBG
  • CBC and CMP

Everyone is a little different, so we often adjust the panel to make sure we get the full picture for you.

Your Program, Step by Step

  1. Consult. We make sure we understand your history and goals so we head in the right direction.
  2. Labs. Our standard panel, customized as needed.
  3. Your plan. Diet, exercise and hormone balancing. Some women want to start with GLP-1 peptides because they are typically the faster route; others want to try without. We lay out your options, and the choice is always yours.
  4. Ongoing adjustments. We walk you through any hormone, nutrient, peptide, exercise or sleep changes and adjust as your body responds.

Insulin Resistance: The Root Issue

Higher fasting insulin blocks your body’s natural production of glucagon and growth hormone, the signals that tell your body to burn fat for fuel. That’s why weight loss feels impossible with PCOS/PMOS, no matter how hard you try.

I never want to deny anyone the education on diet and exercise. That information can be life changing. But my primary goal is to correct the issue as fast as possible. There is no reason to let a problem linger for 6+ months if we can deal with it in 6 weeks. We often use GLP-1s along with nutrients like minerals and myo-inositol.

How to Eat

Eat low glycemic. Reducing insulin spikes helps reduce insulin resistance. That doesn’t mean giving up your favorite foods. Any diet that makes you give up your favorite foods is unsustainable. Remember: it’s not the calories, it’s the chemistry.

Where GLP-1 Peptides Fit

Anyone with insulin resistance, at any level, or with higher visceral (belly) fat can benefit. Diet alone is often enough, but resetting the metabolic hormones with GLP-1s like tirzepatide or semaglutide is faster and quite often needed to restore normal metabolic health.

Acne, Facial Hair and Hair Thinning

Better nutrient intake helps the body handle the vast majority of these issues. For hair loss, the right option depends on the cause: nutrient deficiencies are corrected by replacing the missing nutrients, thyroid issues are addressed with thyroid hormone and the nutrients that make it work at the cell level, and DHT-related hair loss may be addressed with prescription options such as finasteride for women who are not trying to conceive.

Cycles, Fertility and Pregnancy

To support regular cycles and fertility, we focus on resetting insulin resistance, balancing hormones (including testosterone, which women naturally make more of than estrogen), making sure you are getting all the minerals you need, and managing sleep and psychological stress.

If you have PCOS/PMOS and are trying to conceive, I recommend going through this process first. A healthier metabolic system is more likely to lead to a healthier pregnancy, baby and mom after birth. (We support natural conception and do not offer IVF.)

What Women Typically Notice

Many women see positive changes within their first two cycles: significant pain reduction, better mental and emotional stability, higher energy, lighter periods and moderate to significant loss of visceral fat. Results vary from person to person.

The most profound stories, to me at least, are always the same. A woman tells me, “You have no idea what it’s like to be curled up on the floor for two days every month for over a decade, and then just have the pain go away.”

— Dr. Matt Chalmers

We work with women all over the US by Zoom, and in person at our Frisco, TX clinic.

PCOS/PMOS FAQs

Yes. In 2026 the name was changed to PMOS, polyendocrine metabolic ovarian syndrome, because this condition is metabolic in origin, and treatment needs to be metabolic too.

Absolutely. How much weight or fat you carry doesn’t really matter when it comes to insulin and metabolic dysfunction.

No. We often see them, but you do not have to have ovarian cysts to have PCOS/PMOS. It’s one of the reasons the name changed. The longer the issue is left to get worse, the higher the chance of cysts, so address it early.

In many women, the underlying insulin resistance can be reversed. Once the major part of the problem is resolved, many women choose to stop the supplements and peptides and maintain their results with diet.

Insulin resistance blocks the body’s ability to use fat as fuel. Higher fasting insulin blocks your natural production of glucagon and growth hormone, which tell the body to burn fat. Fixing insulin resistance helps reset the body and allows fat loss.

No, and it’s often not the best option. Proper hormone therapy, IUDs, better nutrient intake, stress management and managing insulin with GLP-1s can all help.

They can be used together. In our experience, many patients are able to reduce or stop metformin within the first few months, working with their prescriber. Myo-inositol is a naturally occurring compound that helps regulate the ovarian cycle. The body wants roughly a 40:1 ratio of myo-inositol to D-chiro-inositol. We often see women at 10:1 or even 1:1, and that always causes problems.

You can, and for some women pregnancy even eases the symptoms. But we have seen many women whose PCOS/PMOS made conceiving far more difficult. If you have PCOS/PMOS, I recommend going through this process before you keep trying. A healthier metabolic system is more likely to lead to a healthier baby and mom.

Many women feel better as the years go on, but untreated, it can take a long time for all of the issues to go away.

Yes, please bring them in. I can’t imagine forcing a teenager to deal with teen life and this at the same time. I can’t imagine a more cruel thing to do to a young woman and the people around her.

Unfortunately, insurance coverage is spotty; sometimes it doesn’t even cover the labs. Most programs run about $2,000–$5,000 over a few months, and financing is available. Because every woman’s body is different, we customize each plan, which affects the final cost. Call 214-446-5300 for details.

Nutrients Dr. Chalmers Often Uses

These are the nutrients Dr. Chalmers most often includes in his PCOS/PMOS plans. Many women also benefit from gut and liver support with our Parasite Cleanse Protocol.

Talk With Our Team About PCOS/PMOS

Tell us a little about what you’re dealing with, and a member of the Pillars of Wellness team will contact you. Prefer to call? 214-446-5300.

Written by Dr. Matt Chalmers, DC, CCCN, CCSP. Medically reviewed by, and medical services provided with physician oversight from, Dr. Deborah Z. Bain, MD, FAAP. This page is educational and does not replace individualized medical advice, diagnosis, or treatment. Prescription options such as GLP-1 medications require an evaluation and are not right for everyone.

*Statements about dietary supplements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.