In this episode, the discussion dives into the complexities of weight loss and body composition, highlighting the importance of understanding how the body processes fat, muscle, and protein. It’s explained that simply cutting calories can lead to muscle loss alongside fat, which is counterproductive since muscle is essential for maintaining metabolism. The key is focusing on losing fat while preserving muscle mass, which can be achieved through high protein intake and strategic fasting.

The conversation also explores the effectiveness of keto diets in managing conditions like diabetes by forcing the body to produce its own sugar through fat and protein metabolism. The episode breaks down how insulin resistance can be addressed by limiting carbohydrate intake, allowing the body to regulate blood sugar more efficiently. This approach not only helps manage blood sugar levels but also supports fat loss without compromising muscle mass.

Lastly, insights are shared on the role of GLP medications, fasting, and proper nutrition in optimizing fat burning and muscle preservation. The potential pitfalls of muscle loss, gallstones, and other side effects from improper dieting or medications are discussed, emphasizing the importance of understanding the body’s metabolic functions for sustainable health and weight management.

Highlights of the Podcast

00:02 – The stage to discuss the calories in/calories out model.

01:24 – A calorie deficit leads to weight loss, while excess calories result in fat gain.

02:41 – Personal Experience with Calorie Reduction

03:57 – Observations on Individual Differences:

05:10 – The role they play in fat storage and metabolic function.

06:49 – Body’s Energy Source – ATP vs. Calories

08:15 – Breaking Down the Body’s Components

09:32 – Sugars vs. Fats in Fat Storage

10:23 – Misconception About Calories

13:57 – Role of Insulin in Absorption

15:21 – High Glycemic Foods and Fat Storage:

16:43 – Glucagon and Fat Burning

18:17 – Why Proteins Don’t Turn into Fat

21:39 – The key is not to lose weight but to lose fat while preserving muscle mass

22:48 – Protein’s Role in Fat Loss

24:06 – Keto Diet & Sugar Production

25:29 – Diabetes & Insulin Resistance

27:42 – Fasting to Restart Fat-Burning

28:53 – GLP-1 Receptor Agonists

32:26 – Macro Counting vs. Hormones

36:31 – Reversing Type 2 Diabetes with Keto

Dr. Matt Chalmers [00:00:02] I was supposed to have somebody on a nutritionist dietician to kind of run through the calories in calories out portion of this. He decided that he didn’t want to show up for the podcast. So I’ll just run through that piece as well. So we start off with what everybody is basically in the whole world is going with is the calories in, calories out model. This is how you get fat. So the calories in calories out model means is that whatever calories you eat put in your mouth and you eat has to equal the amount of calories you burn or else you get fat. So the idea is that if you’re in a calorie deficit, you will lose weight. If you’re in a calorie excess, you will gain weight. And so the idea is you take a look at your plate and you add up all the calories that are on your plate. And then if you eat everything on the plate, all the calories that you eat, go in and you count those for the day. And if your magic number is 2500, if you eat 2600 calories, you get fatter. If you eat 2400 calories, you get thinner. So that’s kind of how calories in calories out works. The idea the premise is that the body runs on calories. And if you get too many calories, you have too much energy. It’s an excess of energy.

Dr. Matt Chalmers [00:01:24] And your body stores that as fat. And so that’s kind of the premise behind calories in, calories out. And, you know, there’s that’s roughly all there is to it. People try to make, you know, all these other conditions and all these other things. But the calories in calories out model is if you’re in a calorie deficit, which is again, less than your body is supposed to have for the day, you lose weight. And if you have more calories, you eat more calories than you’re supposed to, then you get fat. And so that’s the thrust. Like, however we want to spit it out. That’s the thrust. So I’ll walk you through my journey with that. So a couple of years ago I was fat and I’d be like, You weren’t fat? I was. I was fatty. Like, I weigh more fat, I mean, than I wanted. It was bothering me. I, I cut my calories down like 15, 1600. My workouts got trashed. I mean, I just couldn’t work out. I was tired. I was grouchy. I didn’t see I didn’t see any fat loss at all. And then people were like, well, you’re in starvation mode. No. Okay. So, so, so now what it is, is that, you know, to get this, if you get starvation mode, your body holds on to everything you consume.

Dr. Matt Chalmers [00:02:41] So what the thinking on this is, is that you’re supposed to eat less calories than you’re supposed to eat during the day. And so if you eat a little bit less, you lose weight. If you eat too few, you can you can gain weight because your body holds on to everything. And so. Okay, so I was eating too few calories. So I have two to like 2600 or something like that. And my workouts got better. I, you know, I was nicer, you know, I was everything was better. So I wasn’t losing any fat, wasn’t really gaining any, but I wasn’t really losing any. And I can go through what I was eating. I was eating a bunch of instant oatmeal. I was eating jasmine white rice, I was eating chicken. I was eating some steak. I had sugar in my in my oatmeal because of all this disgusting and terrible. I’ve always hated it, but that’s what I was going to eat, you know, oatmeal, white rice, chicken, that type of stuff. So I was eating lots and lots of that and didn’t really have an effect on losing fat. And so I started looking at kind of what was going on. And I’m like, Man, I can’t figure this out, you know? And I have a buddy who I’ve known for a long time since college, and I’m very rich.

Dr. Matt Chalmers [00:03:57] He can eat at least during college, even to this day, to a degree, could eat damn near anything he wanted and not gain any weight. And, you know, I started thinking about that and I was like, man, everybody knows a guy or a woman who seems to be able to eat whatever the hell they want. Make rich. You would eat like legit, like a giant pizza. He’d have, you know, 20, 15, 20 beers in a night. And then we’d all be, you know, we’d all swing over to Taco Bell and he’d get, you know, the same thing, or more than I would the double taco Taco Supremes and the, you know, all that type of stuff and have 2 or 3 of those. And, you know, you know, every time I saw him, he’s eating never gained an ounce. And so when I sort of thing about that people like well you know that happens and you know it’s just they have a higher metabolism calories work the same in them and they work in you they just have a higher metabolism. You know, Then I was looking and I was like, Man, I got buddies who eat a lot more than me, a lot more calories than me, and they’re thinner than me. And I got guys who eat the same as me and they’re thinner than me. I got guys who eat roughly the same as I do, and they’re fatter than me. So this doesn’t make any sense to me. If calories are the standard, right? If you know, if that’s the standard that a thousand calories should work the same in me is it works in everybody else.

Dr. Matt Chalmers [00:05:10] Nobody should have a faster metabolism like cause if they have a faster metabolism, then it isn’t a calorie issue. It’s a it’s a metabolic function issue. So it’s like, all right, cool, let me look at this metabolism thing, right? So if I’m trying to speed my metabolism up, right? So like, well, maybe that’s what I got. I got I got to speed up my metabolism and then I lose fat just like my buddy Richie. All right, cool. So if I’m talking about metabolism, we’re talking about metabolic biochemistry, metabolic function. And so I was like, cool. All right, I’m going to start looking at the metabolic chemistry of what this is. And when I found out really quickly was that metabolic functions ruled by hormones. And I think that’s, you know, not you’re going to I don’t know if you can debate that it is is pretty solidly ruled by hormones because this would tell somebody what to do. And, you know, there’s a lot of hormones that come into play. And I had to learn all of them so I could figure out how they all play together. You know, estrogen, progesterone, testosterone, dihydrotestosterone, growth hormone, insulin and glucagon. Now, the last two insulin and glucagon, your major players when we talk about metabolic function. So but again, I was trying to figure out, okay, how do these how do we how do the excess calories make me fat? And so I was looking at the chemistry and I couldn’t find anywhere in the metabolic chemistry. We’re talking about calories, which is weird to me because like I’m looking at metabolic biochemistry, calories run the body. You guys think they’d be here somewhere? They weren’t. I couldn’t find them anywhere in the chemistry. And I did find something called adenosine triphosphate or ATP, which is made in the mitochondria, which you might remember from high school. Biology is the powerhouse of the cell.

Dr. Matt Chalmers [00:06:49] It makes the power for the body to run on, which is ATP. So like I said, I couldn’t find calories anywhere. And I was like, Well, all right, this is weird, but it’s okay, so let’s just go With the body runs on ATP, not on calories. And let’s look at how is ATP generated? ATP is generated in two ways one through sugar, through the Glycolytic pathway and one through fat, which is the type of lytic pathway. So nothing new at this point. We have all pretty much new there. The body runs on either sugars or it runs on fat. All right, fine. Well. How do we how do we lose the fat? You know, because people talk about losing weight and that’s great. And I that I really don’t care about losing weight. I want to lose the fat because I want to lean out. Right. And so I kind of bucketed weight into different categories. So one was fat, one was muscle, one was bones and viscera and one was like inflammatory chemicals. And so this is how I cut the body up. Like you can sort of body however you want, but that’s how I cut mine out because could I wanted to be I have control over each one of them so inflammatory chemicals super easy detox those out of body loses all that water weight cool bones and viscera. I mean you can do a little bit, but not very much. So just kind of scratch that one muscle. Well, I wanted to keep my muscle so I if I weighed 253 pounds and I was, you know, 5% body fat, I’d be fine with that. So, you know, if I had shiny amounts of muscle, I was all right. That’s fine. I don’t really care about that.

Dr. Matt Chalmers [00:08:15] The fat was what I cared about. And so I kind of reverse engineered it and I was like, Well, how does the body make fat? And I’ll save you a lot of the biochemistry. But one of the ways the body makes that is that when you eat fat, your body kind of absorbs that and then stacks it over in the side. So again, I don’t think anybody is, you know, no, no crazy new news that if you eat fat, your body can store it as fat. So, okay, we’ll leave that one to the side. The one that I found was that the fastest way your body actually makes fat is through sugar. So you might take sugar and as glucose and then it converts it into, you know, through the glycolytic process, it breaks it down into some pieces and then it turns into basically glycerin and then it turns into it ends up in a tag, which is to try acetyl glycerin. Once it’s there, it can then be differentiated into whatever else the body is going to do with it. So that’s where your LDL, HDL, that’s where all those things come in. But basically, once it gets converted into that, it is stored as fat. So sugars turn into fat and say, all right, cool. So sugars are fat. Now, that’s that’s a pathway which I think is still obvious.

Dr. Matt Chalmers [00:09:32] You know, if you eat too many sugars, you’re rising store that excess as fat. So sugars and fats we now have coming in. And so I looked I was like, okay, well how much you know, how much how to proteins turn into fats? Well, here’s where the rub comes in. There’s only one way that a protein can become a fat. Your body would have to turn it into a sugar, which it does all the time. It’s called gluconeogenesis. And then you’d have to have so much glucose that the body would then raise the insulin levels enough that it would start storing that glucose as fat. Because remember, the glycolytic pathway is ruled by insulin. There’s the hormone for for for that. And the fat hormone that rules the fat is glucagon. And so what ends up happening is that. You know, there’s a couple different problems I have with the caller system.

Dr. Matt Chalmers [00:10:23] One, the caller system says it was what is the energy that he runs on? That’s not true. That hey. And then it tells you that this energy, if you could get too much of these caloric energies and it turns the fat. So. The problem is, is that the definition of a calorie is the amount of energy required to heat one kilogram of water, one degree Celsius. So we have a couple of problems now there. So what you’re telling me is it’s a unit of energy. Okay. So what would have to happen for calories to become fat is that calories have to go through energy to matter conversion. Thus the energy you’re having in magically through. However, we’re going to talk about Star Trek. Star Wars type stuff turns into matter because you can hold fat in your hand. You cannot hold calories in your hand. So the only way for calories to turn into fat is to figure through energy to matter conversion, which isn’t going to happen. The other thing is, is that calories are never expressed in the body because for a calorie to be expressed, you have to heat water one degrees Celsius.

Dr. Matt Chalmers [00:11:26] So if you eat 2000 calories and your body temperature never rises, calories haven’t been expressed because the way you measure it is the water. The temperature of the water was 98 degrees. We ate, we added ten calories and it’s now 108 degrees. Okay. So if your body temperature doesn’t get hotter at all, you know, calories are expressed. You’re measuring it in calories. It’s like today it’s 70 degrees outside. If it got hotter and we get to 80 degrees, we the difference is ten degrees. That’s the thing. If if the temperature doesn’t go up, no calories are expressed. So we have that issue as well. And so what we have to start finding out, we start looking at is that, okay, so how does the body deal with these sugars that it’s turning into fat? The way that this process actually works is through insulin. And one of the other problems we have, the calorie system is that, like I said, if there’s a thousand calories on your plate and you eat 2000 calories, you have to account for the thousand calories, which also doesn’t make any sense because the way that we look at the body medically is it’s not what you put in your mouth. It’s what’s absorbed across the intestinal mucosal because of line.

Dr. Matt Chalmers [00:12:40] So it’s actually not from your mouth to your anus is not inside your body. It’s in your digestive tract, which is technically outside your body. The only things that are in your body are what we absorb through the intestines. So this brings up another problem. If you eat 2000 calories and 100g of that is insoluble fiber, that is 400 calories. That is 20% of everything you ate that day. That doesn’t ever get inside your body. So we now have to realize, okay, so Absorber to Function is a major player in how we get fat. Okay. So, you know, if you’re going to count the calorie system and you’re look at insoluble fiber, you’re going to count those 400 calories that never made it inside your body, but they went inside your mouth. So now we have that issue as well. So, you know, insoluble fiber is very, you know, very functional for what we’re talking about because there’s a lot of ways you can use inside will fiber to, you know, allow you to have foods you like chips, pizza, tacos, like all sorts of things. So that’s the issue we run into. And so. That’s one of the other problems we’re in. Okay. We’re. We’re counting this wrong. Well, the other thing is that what we all have to understand is that the way things get into the body through the intestinal mucosal membrane are also through insulin.

Dr. Matt Chalmers [00:13:57] And so and this is actually how you fix diabetes. I’ll walk through that in a second. But we have to understand that because when we start to have insulin resistance, it’s because when we eat a carbohydrate and you’re right, it goes, there’s sugar. We need to increase the insulin so we can bring that sugar in. When that happens, it moves from the intestine across the intestinal mucosa membrane into the body. This is very, very important. So keep this put a pin on this and hold on to it later. So that’s one of the problems. So if you’ve had a lot of carbohydrate function or a really high glycemic curve carbohydrate function, the glycemic function is how quickly a carbohydrate turns into sugar. So back when I was talking about I was eating a lot oatmeal and all that. Incidentally, on the instant jasmine rice, massive giant glycemic numbers on that. So it turns of sugar almost instantly and a giant amount of it. And then if your insulin levels have been high because you have lots of carbohydrates. So your fasting insulin is 16, 17, 18, 20. The amount of sugars you’ll actually pull across the intestine because the membrane is a lot higher than you would normally. This is how, you know, insulin resistance creates giant problems. And it’s not so much insulin resistance to the cell. What ends up happening is that your body literally starts producing more insulin than it’s supposed to than something it needs. And so what ends up happening is that you’re sucking all the sugar in. And so all of a sudden it’s in your blood.

Dr. Matt Chalmers [00:15:21] Well, what does your body do with blood? With a sugar that’s in your blood? It will go to feeding the blood and feeding the brain and that type of thing. And then it will go to feeding the muscles and then whatever glucose that’s the sugar is your blood. Whatever glucose is left over will end up staying stored in the muscle tissue as glycogen. And then it moves back around the whole body and it gets the liver and it stores this glycogen in the liver. Any excess on top of that that it doesn’t need because it has to pull out. The blood will then be converted into fat. And so that’s how your body regulates the amount of sugars that’s in it. And so that’s that’s where you’re going to see of the sugars turning into fats. Now, the way that your body processes these chemicals, the way that you read this, the actual functional sensitivity that you have to insulin is going to increase the amount of fat stores that you happen to have. So that’s how we store the fat. So the question is, all right. So how do we get rid of the fat? Well, the way that your body actually gets rid of the fat is, again, tied directly to glucose. So as glucose levels in the blood start to fall. So we have what’s called we have a decrease in Glycolytic ATP. So ATP that is produced from glucose as those little start to fall, the alpha cells of the pancreas, the little little cells that make glucagon as the glycolytic ATP level start to fall.

Dr. Matt Chalmers [00:16:43] It shuts down the calcium channel intake, pressure builds inside, and it puts pressure on onto the glucagon receptacles, and the glucagon then kicks out in the bloodstream. So now what does glucagon do? Glucagon job is to initiate is to partner with burning fat. And so your body knows burning fat for ATP creation instead of sugar. And so that’s where the glucagon comes in. Now, the fun thing about glucagon is it also helps initiate a process called gluconeogenesis, where your body creates new sugar. It creates it out of it uses the light pathway to burn fat while it takes apart proteins and uses the proteins, the amino acids and the carbon skeleton from the protein to then go through a process in the liver called gluconeogenesis, where it makes new sugar for the body. Now, what happens to the blood sugar at this time? Is this the blood sugar starts to drop, the liver starts to feed the blood sugar. So it’s dropping glucose into the sugar to normalize blood sugar levels. And as the liver starts to run out of sugar, we start refilling the levels of sugar in the liver with the gluconeogenesis. So that’s how that happens. Now, here’s the rub. Here’s why. Proteins will in the second will never become fat. So what ends up happening is that once your body starts hitting the point where it is, okay, we have we have corrected the levels of sugar in the blood. We’ve corrected the levels of sugar in the muscles and we’ve refilled the liver with glycogen.

Dr. Matt Chalmers [00:18:17] Once those levels get where they’re supposed to be and you start having glycolytic ATP creation again, your body stops producing glucagon. And it starts it starts producing insulin. Insulin stops the process of glucagon function. And so what ends up happening is that as you’re taking apart the proteins to make the sugar, you’re never going to get to the point where you have so much sugar from the protein that you’re going to actually stored as fat because as the insulin levels start coming back up. It inhibits the glucagon and actually stops the process of sugar creation. So you’re just never going to get to the point where you have enough sugar to store. And so that’s how that process works. Now. The way that you can kickstart this. This function is to cut back on your carbohydrates as you cut back on your carbohydrates more and more and more. What ends up happening is that the amount of time that your body has to spend using using fat and proteins to make its own sugar called that endogenous sugar sugar made inside the body, then what ends up happening is that the more fat you actually burn now.

Dr. Matt Chalmers [00:19:23] Let me go back to the you know, the people who one guy is really thin. One guy, you know, is kind of moderate and one guy is super fat. This is called as a matter of typing. And this is basically the easiest way to explain. This is how sensitive is this person to the two hormones, glucagon and insulin. So the guy at the at the one end of the table and this is we never talk about this guy when we talk about weight loss, we talk about energy management. We talk about this sort of thing. No one ever talks about the guy who cannot gain weight. Like everybody is talking about, like, I’ll help you lose weight. Come to my program, you’ll lose weight. There’s not a whole lot of hey, can you not put any muscle mass on? Can you not grow? There’s not a whole lot of, you know, even acknowledgment that there are people who are their primary concern is that they can’t gain weight. So because we have excluded these people from the conversation and we don’t recognize they exist. The only thing we think of is the measure morphs, which and those are the guys which you restrict their fuel source, whether it’s fats or carbohydrates, and their body will start burning more fat. So these guys can cut their calories back or cut their fuel source back really easily and they start to lose weight.

Dr. Matt Chalmers [00:20:27] So that’s the middle guys, the guys on the very far end. You have to actually do work to get into more sources where I live. You have to do work to get those guys to increase glucagon function so the body will actually start burning more fat. So that’s kind of how that that’s similar type system works. And so a lot of times in this smarter typing system, if you look at the amount of type research, what you find out is that glycemic function, it plays a giant role in this. And so guys who are wild acto morphs, who can’t gain weight if you give them really high glycemic foods, orange juices, juices, you know, the white rice, the instant, you know, oatmeal, like the things that have really high glycemic function, the things that produce a lot of sugar, the things that produce a lot of glycemic function and thus a lot of insulin release. That’s typically the easiest way to get these guys to gain weight. Not always, but that’s typically what we see. Well, if you restrict that, that flow on the endo morphs. So you take away all of our sugars. That’s why these guys lose weight. So that’s why keto diets work really, really well for fatter guys. Now they’ll work for everybody across the board because the mesmo morphs. They the same biochemistry runs their bodies from somebody else. Now, here’s the thing.

Dr. Matt Chalmers [00:21:39] Remember, we started breaking down weight and we talked about there’s fat, there’s water, there’s muscle. So here’s the problem. A lot of times and mesmo morphs are in, you know, whatever. If you’re ruling it by calories and this is a big thing we see in the bodybuilding community. We if you’re ruling your diet by calories, when you cut your calories way back, you get your fuel sources way back. What ends up happening is your body burns through all the carbohydrates. First of all, the sugars real fast back out and then it goes, okay, we need a lot more energy. We need a lot more ATP. And so we’re going to start making it from fat. And so, yeah, you start burning the fat, but remember, to make sugar, you have to have proteins. Well, if you didn’t eat enough protein, where’s the body going to get this extra protein? It gets it from your muscle tissue. So it tears apart your muscle tissues to get the proteins in the amino acids it requires to go through gluconeogenesis, It burns the fat that’s on your body. So, yeah, you lost a lot of weight. You may have lost 5 pounds of fat and 5 pounds of muscle. So that’s the thing that you have to keep in mind is that you don’t want to lose weight. You want to lose fat. So you want to keep the muscles because the muscles where the ATP live, that’s where your metabolism actually lives.

Dr. Matt Chalmers [00:22:48] So monitoring that is important because now that you understand that you can eat basically as much protein as you want and you’re not going to turn that into fat. Well, now you have the keys to not lose muscle mass while you’re losing fat. Pretty easy. In fact, you can build muscle mass really easily on a on a fast. I was running a 47 one fast weight once every 48 hours. And I was putting on muscle tissue like crazy and burning burning the fat off. So like this year, I’m right at between 35 and 40 pounds of fat. It’s lost that muscle. It was gained because the scale is actually up a little bit from when I started in January. But I am much, much bigger than I was in January and much, much more. It’s cutter much more cut. And so that’s kind of where where that that piece lies in the amount of typing. He’s got to look at the glycemic function. But this is also like keto diets work so well it’s not because your body you’re taking something away that your body needs. You’re just. Not giving it from an outside source. Your body still has to have sugar, so your blood can only run on sugar. So people like your whole body can run on ketones. That is 100% not true. Your blood has to have sugar. It’s just that. Where are we going to get it? Are we going to make it ourselves or are we going to bring it in from an outside source? So that’s where that comes in.

Dr. Matt Chalmers [00:24:06] Your blood has no mitochondria, so it can’t produce ATP. And so it has to use what’s called Sata, lytic ATP, where as the glucose comes across the cell membrane of the red blood cell, it splits into 2 to 2 molecules of lactate. And when it does that, it releases two ATP. So that cytoplasmic ATP duration comes from the sugars. And so that’s why we have to make sugars here in the blood. So that’s how the whole process works. And so when we start looking at keto diets, we’re like, okay, so we’ve restricted all the carbohydrates. And so your body has to literally make its own sugar. And so it’s making it from the protein you’re eating and the fat you’re eating and the fat that’s on your body. So that’s how that works. That’s why people who go in Quito lose so much fat so quickly, but they still maintain that strength and things like that. Now, I told you that we talked about how we fix diabetes. Diabetes is where it’s basically insulin resistance gone awry. It’s way big, big, big. And so, like, you test these people, these people’s insulin and it’s 17 to 25. I’ve seen 30 on fasting insulin levels. And so what you do is you. All right, cool. We’re going to strip all the sugars out and we’re going to make your body produce it indigenously. And so what you end up seeing is you see these, you know, blood sugar numbers that are way off the chart. You strip them of all that. You don’t have to put them in the keto diet, but putting them in today, it’s the easiest for everybody.

Dr. Matt Chalmers [00:25:29] So that’s usually what we do. Put them in a keto diet and all of a sudden their body, their blood sugars come back down to basically normal because their body has to make it themselves. Now, here’s the problem with normal. You have to understand, like even for people who are akito, there’s something called the dawn effect. And so a lot of times what will happen is people be on Kito to be on Carnivore and they’ll get their blood drawn. The fasting, everything’s great. They get their blood dry in the morning and their blood comes back hundred and 20, hundred and 30 blood sugar. And people were like, my gosh, you’re diabetic. Okay, we need to stop and look at this for just a second. The amount of sugar that’s in the blood is not what we need to worry about with diabete diabetes, because the amount of sugar that’s in the blood is fine. The sugar itself is fine. The control. The regulation of the sugar. Is the problem. Well, what controls and what regulates sugar insulin. So again, you’ve got a pull fasting insulin, which nobody has on diabetes has done because I see these blood reports all the time and nobody pulls insulin. So again, you put them into a keto diet.

Dr. Matt Chalmers [00:26:33] Their body makes the sugar for them and let the body make as much sugar as at once. If it wants to sit at 130, 140, let it because it’s not going to do it for very long because again, it’s still going to manage all that stuff from a glucose glycogen function on the inside. So what you see over time is that not only do the fasting insulin levels come down, but the blood sugar levels come down and they normalize. And so that’s the way that we’ve done it. Now, oftentimes people who’ve been stuck in the sugar stay for a long, long time have a problem converted going from, you know, super sugary into fat burning state. Okay. The way that you can kickstart glucagon production is with fasting. And so you tell the body, look, you’re not going to get anything and you’re going to make all the stuff yourself. Like you got to pull all the fat off you. You get to like, I use collagen and stuff like that. But oftentimes just let it eat the muscle tissue because you can rebuild it pretty easily. So, all right. You’re going to make everything yourself. So we’re just going to fast and for a couple of days, usually it takes 48 to 72 hours, give or take, on the individual when they’re ready to start producing glucagon again, because it has to it has to start producing blood sugar and it has to start doing that by burning fat.

Dr. Matt Chalmers [00:27:42] Now there’s there’s a walk through that I usually do with people so that they understand what’s going on. The other piece of that is that if someone’s been running sugar system for a long, long time, you have to understand when they change gears and they start producing it via fat, this is kind of a muscle. They have an exercise in a long time. So getting it to work efficiently and well can take a minute. So that reflects in a couple of ways. Some people lose a giant amount of fat real fast. Some people have like the keto flu. As they start going through it, they start having detox issues. They start kind of feeling blah again. You need to walk them through that because lipo lytic function requires a variety of things that glycolytic function doesn’t. So for instance, it requires the production of a giant amount more bile salt. Well, if you don’t have methylated B six, you’re not going to reduce bile salt properly. You’re going to you’re going to lose congealed bile salt that we you know, that’s going to end up turning into liver stones, which is when they’re dropped from the gallbladder, they’re squeezed together to larger liver milestones. And we call them gallstones, which is one of the things we see with a lot of GLP six GOP agonists like Semaglutide and stuff like that. And so that’s the big piece. So you’ve got to like you’ve got to kind of manage that.

Dr. Matt Chalmers [00:28:53] You’ve got to make sure that as you’re pulling them into this, you’re starting to manage the, the, you know, creation of ATP via fat, that labile pathway that the body has, all the chemistry it needs. The liver is clean, lots of B vitamins. It’s had all the, you know, all the all the nutrients and all the chemicals it requires to go through the process, know all the ADHD and all that stuff. You’re to have all those all those chemicals that are in the life like pathway to do it safely. So that kind of brings up, okay, so how do how does how does the GOP stuff work? Well, the way some big blue tide works is it is it activates the GLP receptor sites. Now, here’s the cool thing about this, because the research on it is actually wrong because it says that it helps your body produce insulin, it helps the insulin kind of manage blood sugar. It doesn’t do that at all, actually does the exact opposite of that. What ends up happening is that it shuts off the gut’s ability to bring in insulin. That’s why it causes the gastroparesis. That’s why it causes the body to kind of the digestive system kind of shut down because it no longer blocks the ability to take sugars through the intestine in the bloodstream.

Dr. Matt Chalmers [00:30:01] Okay. Because if you take in a bunch of sugar while you’re doing this, it’s going to throw off your body’s ability to regulate what it’s actually making. And so it shuts off your body’s ability to bring in excess glucose, extra glucose from an exogenous source while it’s producing the sugars from the endogenous source so it can know how to stop. Okay, so that’s more or less what’s going on. So that’s how it’s these diabetics are taking it and they’re losing all this weight. That’s how these people are taking it. They’re losing all this weight. But again, remember, what are the problems with GLP? Gallstone issues, societies, Right. So that type of stuff. And then we have massive muscle, muscle wasting. You know, they found in some of the research studies that 40 to 50% of the weight that was lost with guppies, it was muscle mass. Well, of course it was, because what did GP’s do? What does glucagon do? It helps your body process and start the process of gluconeogenesis. This is going to tear apart proteins. And it’s going to make sugar out of them. If you’re not eating enough proteins, oftentimes it’ll eat the muscle tissue that you have.

Dr. Matt Chalmers [00:31:09] Now, the other thing that we’re told people don’t talk about is that it also radically for a lot of people, not everybody, for a lot of people, radically reduces the amount of food that they want to eat. Because, again, it makes your stomach feel full all the time. I know people who are they’re like, even taking the supplements makes me feel like I’m going to throw up because I ate too much. And I’m like, Yeah. So you bring in a lot less food. And so people are like, See, it’s calories, but it’s not. It’s it’s sugars and it’s, you know, it’s fats. So that’s, you know, it’s a biochemical function to macro function. And some of it’s not like energy from from calories function. So you didn’t bring enough enough protein. So you really had to utilize the protein had access to, which is your muscle tissue. That’s why you lost it. So that’s that’s how the system actually works. Now, if you’re working on people, who are those those Muslim guys? Yeah. I mean, you can cut back total fuel and it’s not that big of a deal. Like you can you can measure yourself with calories and that’s fine. Like, it’ll work. The problem is that it won’t work to put muscle on or wait on the guys who are on the actor side. And it won’t work to pull fat off of the really fat guys. Now, and this is where we get into the whole like the trainers always, right And the trainers perfect And you know it obviously if you’re not losing weight and you didn’t do my calorie deficit program.

Dr. Matt Chalmers [00:32:26] Right. Because you know it’s flawless and that’s how it works. And so we count calories back and you lose the fat. That’s how everything works. And if you didn’t lose weight when you did the did that the plan, then, you know, you didn’t really run it. You cheated. You know, you you ate too much. You didn’t really follow it. And. And the defense of all the trainers out there. That happens a lot. However. There’s also the case where people do exactly what you say and they don’t lose any fat. They don’t lose any weight because, again, it’s a hormone driven system. It’s based off of sugars. Sugars becoming fat and fat. Becoming fat. So, you know, the way that you can push this together is this is how I do mine. Like I tell people like, bring your ten favorite foods and I’ll build a diet out of it. And we were like, all right, tacos and pizza and brownies and cookies. Fantastic. Super easy to do. All right. Because, like, you make a brownie that has no glycemic function, so there’s no sugar in it. Nothing turns into sugar. And you’re good to go. Like, lots of protein, stuff like that. You know, almond flour has fat in it, but then we do it back to the absorber to function with fiber.

Dr. Matt Chalmers [00:33:34] And so you kind of have to factor that in. So, you know, you’ve got almond flour, you’ve got eggs, butter. You’ve got, you know, sort of a sweetener monk fruit, erythritol like that. I think those are my favorites among fruit. And Arthur talk is, first of all, is really, really awesome for your blood system, your cardiovascular system. And so, you know, in Kcal. And so you have this really actually, really healthy thing that tastes like brownies. And so it’s super easy to get people to be like, okay, now here’s the thing again. I never said that you could eat whatever you wanted to. It’s a fuel system. How much carbohydrates and how much fat are you bringing in versus how much you’re burning so that actually that that function is actually real. So but the thing is, is that if you bring in a ton of protein, like, you know, look at smoked turkey, smoked turkey has no carbohydrates. It has very little fat, it has a lot of protein. You can eat giant amounts of smoked turkey before it does anything to your waistline, but make it go down because again. Proteins and amino acids have been shown to increase glucagon production.

Dr. Matt Chalmers [00:34:38] So again, eating the protein helps increase glucagon function, which is how your body’s going to create sugar for your body and burn fat at the same time. So, you know, so that’s that’s more or less how it works. And again, you know, you can use GP’s if, you know, to, to fix diabetes, you can use ketone, fasting to fix diabetes. The real thing is, is that you pull the pull the into fasting insulin and then you work the diet in a manner where you have you drop the glycemic intake so low that the body has to first eat up all the sugar that’s sitting around it and then it has to start producing dumping sugar from the liver into the body. Then it produces glucagon and then it starts refilling the sugars that your body is using via the liver. And so that’s where the system starts and that’s where you start to see diabetes kind of going away. Now, here’s the cool thing. If you’re like, well, I want to go back to eating the sugary stuff, which so far nobody has actually wanted to do. I want to be walking through it. But all right. So how do we how do we actually fix the diabetes? And this is this is pertinent for all type tests. And some people who are diagnosed, type one, you’re not really type one. You’re just a late stage. You’re just an early stage type two. So ends up happening is that the body was designed and created to heal itself. And so if we just give it the chemicals it needs or and sometimes take away the chemicals that it doesn’t need, we can resolve this issue. And so what ends up happening is that your body without the insulin production or very, very, very, very low insulin production, the insulin receptors on your intestinal mucosa and on your tissues, on your inside, in their internal cells, your liver, your, you know, your kidneys, your your muscle tissues, all that stuff, those receptors can start to heal and regenerate. And so after about 90 days, give or take, everybody’s a little bit different.

Dr. Matt Chalmers [00:36:31] After about 90 days, your body has healed itself. And so you can start consuming the lower middle level, lacing the carbohydrates now, and you’re not going to have diabetic issues on top of it. I would tell you that about 30 to 40% of the diabetic population right now, if they just went keto, they would have little to no issues being keto going kiddo and having it fix their diabetes, which leaves a giant amount of like 60 to 70%. They need a little bit of walking through it. So, you know, it’s one of those deals where if you’re diabetic and you’re like, Hey. Okay, that that makes some sense to me because I keep hearing about people fixing their Type two diabetes by changing their diet. I just never understood how it worked. Well, that’s how it works. And so if you wanted to go Quito and try it, you can now it will technically work even if you do dirty Quito. But the problem is that if you’re doing dirty Quito and eating things like Sucralose and stuff like that, you’re going to create secondary problems down the road. So learn how to Quito properly and eat the clean fats, the clean sugar alternatives and that sort of stuff. So that’s that would be my $0.02 on that one. And how that goes in that that’s that’s how this thing really works.

Dr. Matt Chalmers [00:37:41] Like I said, the way the reasons confusing is that the calorie model does work really well for about 30% of the population. The people population that’s Meza morphs into. The other thing that’s interesting about the matter of typing real quick is that it’s not a set point. It’s not one, two and three. It’s an it’s an infinite array of sensitivities, you know, between actor morph and metamorph. And so you can be acto, you can be acto Mazo, you can be mazzucato, you can be mazo, you can be mazo indo, indo, mazo or indo. Like those are just some of the differentiations in there. So this is why, you know, some people, you know, can eat, you know, something and they get a little bit fat and the other person doesn’t eat that at all and the person gets really fat is because the radiation of how your body utilizes or how sensitive it is to the two hormones, insulin, glucagon matters a tremendous amount more than the amount of calories you consumed. So, again, it’s a hormonal piece. So, you know, what’s funny is that people are like, hey, it’s all about calories in, calories out, but you need a high protein diet. Why? Well, because we find out that high protein diets help you lose fat. Well, I explain to you how. But doesn’t that seem a little silly? Because if we look at how we’re counting the calories to begin with, it is for calories, for carbohydrates and for calories for protein. So you’re telling me that in this counting system where we just count up how many calories we’re eating and that tells us if we get fat or not, the thing that produces glucagon, the thing that creates fat burning, the proteins are counted the same way as the sugars, the thing that makes the body create fat chemically.

Dr. Matt Chalmers [00:39:22] So this was this is one of the problems I’ve got with it is you’re telling me that, you know, we’re going to count these things up and at the end of the count, if we have too much, we get fat. If we have too little, we lose fat. And you’re telling me that the thing that makes that chemically and the thing that burns fat chemically are counted the same way in the same amount? I can tell you your system is broken. And that’s that’s what that’s where my argument is on the calorie function. So that’s kind of what’s going on as far as those things go, especially because you’re saying that sugars for. Insoluble fiber, also for calories. The insoluble fiber we just discussed never gets inside the body, so it shouldn’t be counted in any way. So, okay, so we now have for that sugar that turns turns the fat chemically for that never gets in the body. And for that burns fat. And so this is how this is how we’re monitoring and doing things right now. So, you know, like I said, yes, the calorie system will work just fine on the middle piece of that little group. The measure morphs who the right is more or less equally. For example, they’re easily they’re equally sensitive to other glucose and insulin. So they build fat and they burn fat pretty much evenly. So if you cut back on what they’re what they’re consuming, their body will eat up the sugars in the blood. And then banks start making sugar for the blood, burning the fat. So that’s basically how they work. Everybody else is not doing that very well. So, you know, they’re either not storing the stuff in the tissue or they’re storing way too much. So that’s kind of how that works. Took me a long time to explain that, but that’s kind of where it’s at. So unfortunately, that that my my nutrition dietician guy who is going to explain the calories in, calories out and then go back and forth on the on where I’m misled or where I don’t understand chemistry or I don’t understand how the body works and that type of thing.

Dr. Matt Chalmers [00:41:14] Decided to show up. So that’s where it’s at. So I’m going to post this. If you guys you know, you guys, you know, they throw it and you’re like, okay, here’s where you’re wrong. Here’s where the calories really do play in. And here’s a chemical equation showing calories and here’s how a calorie actually becomes a physical thing and becomes fat. So here’s this. I would love to know because this is the system I’m using. And while it’s working really, really well, if it’s not really the system we should be using, I want to make sure that I’m using the right system to work on people and get them healthy. So. That’s where it is. All right. You guys have fun. And thanks for your time.

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